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THE MEAT & Potatoes

Testosterone Boosters - The Most Important Supplement For Men

Plenty of things are sagging and dropping these days, but even worse than some parts of your body or the stock market is your level of total testosterone. Testosterone levels have decreased steadily for decades among young U.S. men between past and current generations. And research demonstrates that the critical male hormone testosterone starts to drop in adolescence – this is not just a problem for men in their 50s. How do you fight back and win the war against low T? Arm yourself with VITAMIN T + NITROTEST. Because testosterone plays a key role in a man’s physical and sexual performance, it’s important that all men address healthy testosterone levels, which is why MuscleMeds developed VITAMIN T & NITROTEST. This pair of supplements provides premium testosterone-support, a complete daily multivitamin, and a heavy-hitting pre-workout specially formulated for men.†  ENHANCE TESTOSTERONE NATURALLY Testosterone has a plethora of important functions. Receptors for testosterone are found in almost all tissues, and it contributes to lean body mass, bone health, cognitive function and mood, and the production of sperm. NITROTEST is a 2-in-1 hardcore pre-workout supplement with natural testosterone boosters. VITAMIN T is a high-potency multivitamin formulated to provide natural testosterone support.† Higher testosterone levels will help you build more muscle, recover faster and perform better in the bedroom. Low testosterone, on the other hand, can result in erectile dysfunction, reduced bone mass and sex drive, loss of muscle, increased body fat and lethargy. Seems like a no-brainer: No man should ever ignore the importance of proper nutrition and supplementation to support healthy testosterone levels for optimal male performance. The research and development team at MuscleMeds has formulated VITAMIN T and NITROTEST with clinically researched herbs and minerals and potent antioxidants to support testosterone naturally, to improve physical and sexual performance.† YOUR T LEVELS ARE DROPPING You may not realize it, but your testosterone levels are dropping as you read this. According to results presented at the 2020 American Urological Association Virtual Experience and reported in Urology Times Journal, testosterone levels have declinedin adolescent and young adult men (AYA) from 1999 to 2016.  Because testosterone plays a key role in a man’s physical and sexual performance, it’s important that all men address healthy testosterone levels. Put another way, today’s men are not the men their fathers were in the testosterone department. And the decline in total testosterone was observed even among men with normal body mass index – so dropping testosterone is happening regardless of whether you are carrying a few extra pounds. Lokeshwar et al. used data from the National Health and Nutrition Examination Surveys (NHANES) from 1999 to 2016 to analyze serum testosterone level changes over time in 4,045 young adult men aged 15 through 39. After controlling for confounders – including year of study, age, race, BMI, comorbidity status, alcohol and smoking use, and level of physical activity – researchers found that total testosterone was lower among men in later (2011-2016) versus earlier (1999-2000) years. Mean total testosterone decreased from 1999-2000 (605.39 ng/dL), 2003-2004 (567.44 ng/dL), 2011-2012 (424.96 ng/dL), 2013-2014 (431.76 ng/dL) and 2015-2016 (451.22 ng/dL). ‘VERY SCARY’ Testosterone deficiency has a prevalence of 20% among adolescent and young adult males. Although previous studies have shown that total testosterone (TT) levels are declining in the population compared to prior decades, Lokeshwar et al. identified falling TT levels for AYA males specifically. “This is especially worrisome in this young adult age group, as many men feel stigma and are less likely to seek care for low libido and erectile dysfunction,” said Soum Lokeshwar, MD, MBA of the Yale School of Medicine. “Testosterone levels in AYA men are used as the benchmark normal levels for testosterone,” Lokeshwar continued. “This is very scary, because generally, when we think of normal values of testosterone, we treat based upon this age group. This may ultimately lead to the undertreatment of testosterone deficiency, which can have large ramifications and severe consequences.” WHAT CAUSES LOW T? Lokeshwar said possible causes for TT declines could be a result of obesity and declines in exercise and physical activity, and higher body fat percentages. “We’ve seen that lower values of testosterone have been associated with increased comorbidities and an increase risk for all-cause mortality. This decline specifically, in these young adult men, with increased obesity may lead to an increase in precocious cancer,” Lokeshwar said, adding such decreases can also result in a lower libido and an increased risk for erectile dysfunction. Other causes of lower testosterone in younger men may include fasting, low- fat diets, ketogenic diets, overtraining, phytoestrogens from soy, alcohol, statins (cholesterol-lowering drugs), chronic stress, lack of sleep, and environmental endocrine disruptors such as Bisphenol A (in polycarbonate plastics) and Phthalates (found in plastics and many cosmetics). For testosterone support, VITAMIN T contains 500 milligrams of Fenugreek, 200 milligrams of Tribulus, 100 milligrams of Longjack and 200 milligrams Boron Citrate.† VITAMIN T also contains potent antioxidants such as vitamins C and E to support the immune system and optimal male health.† LOOK, FEEL AND PERFORM AT YOUR BEST The choice is yours: you can get up every day and choose to be the best version of yourself possible, directing your own course in life to one of optimal health and performance. If you want to look, feel and perform at your best, VITAMIN T is the multivitamin for you. †These statements have not been evaluated by the U.S. Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. References:1. Naghii MR, Mofid M et al. Comparative effects of daily and weekly boron supplementation on plasma steroid hormones and proinflammatory cytokines. Physiology and Pharmacology 2011; 15 (3), 403-414. 2. Kristie L Kahl. Urology Times Journal, July 3, 2020; Vol 48 No 7, Volume 48, Issue 07. 3. Soum D Lokeshwar, et al. Decline in Serum Testosterone Levels Among Adolescent and Young Adult Men in the USA. Eur Urol Focus, 2021 Jul;7(4):886-889. 4. Shufa Zheng et al. Serum level of testosterone predicts disease severity of male COVID-19 patients and is related to T-cell immune modulation by transcriptome analysis. Clin Chim Acta, 2022 Jan 1;524:132-138. 5. A Klibanski et al. Reproductive function during fasting in men. J Clin Endocrinol Metab, 1981 Aug;53(2):258-63. 6. Tatiana Moro et al. Effects of eight weeks of time-restricted feeding (16/8) on basal metabolism, maximal strength, body composition, inflammation, and cardiovascular risk factors in resistance-trained males. Journal of Translational Medicine, volume 14, Article number 290 (2016) 7. Anthony C Hackney. Hypogonadism in Exercising Males: Dysfunction or Adaptive- Regulatory Adjustment? Front Endocrinol, 31 January 2020. 8. DM Kelly et al. Testosterone and obesity. Obes Rev, 2015 Jul. 9. M Diaz-Arjonilla et al. Obesity, low testosterone levels and erectile dysfunction. Int J Impot Res, Mar-Apr 2009. 10. Mark Ng Tang Fui et al. Lowered testosterone in male obesity: mechanisms, morbidity and management. Asian J Androl, Mar-Apr 2014. 11. Overweight men can boost low testosterone levels by losing weight. Endocrine Society; June 25, 2012. 12. Haibo Jin et al. Chronic exposure to polystyrene microplastics induced male reproductive toxicity and decreased testosterone levels via the LH-mediated LHR/cAMP/PKA/StAR pathway. Part Fibre Toxicol, 2022. 13. Pai Zheng et al. Association between ambient air pollution and blood sex hormones levels in men. Environmental Research, Volume 211, August 2022. 14. Reduced testosterone tied to endocrine- disrupting chemical exposure. Endocrine Society, August 14, 2014. 15. Ylenia Duca et al. Substance Abuse and Male Hypogonadism. J Clin Med, 2019 May 22;8(5):732. 16. Tzu-Yu Hu et al. Testosterone-Associated Dietary Pattern Predicts Low Testosterone Levels and Hypogonadism. Nutrients, 2018 Nov; 10(11): 1786. 17. Joseph Whittaker et al. Low-fat diets and testosterone in men: Systematic review and meta- analysis of intervention studies. J Steroid Biochem Mol Biol, 2021 Jun. 18. Hideyuki Imai et al. Secondary Hypogonadism due to Excessive Ingestion of Isoflavone in a Man. Intern Med 2022. 19. Maarten C Bosland et al. Impact of 18-Month Soy Protein Supplementation on Steroid Hormones and Serum Biomarkers of Angiogenesis, Apoptosis, and the Growth Hormone/IGF-1 Axis: Results ofa Randomized, Placebo-Controlled Trial in Males Following Prostatectomy. Nutr Cancer, 2022;74(1):110- 121.20. Xiaofan Xiong et al. Chronic stress inhibits testosterone synthesis in Leydig cells through mitochondrial damage via Atp5a1. J Cell Mol Med, 2022 Jan;26(2):354-363. 21. Sleep loss dramatically lowers testosterone in healthy young men. ScienceDaily, JAMA and University of Chicago Medical Center, June 1, 2011. 22. Rachel Leproult, Ph.D. and Eve Van Cauter, Ph.D. Effect of 1 Week of Sleep Restriction on Testosterone Levels in Young Healthy Men. JAMA. 2011;305(21):2173-2174.  

Stem Cells & Muscular Strength, Hypertrophy, and Injury Prevention

We all know that physical exercise is essential for maintaining a healthy body and mind. But to get the most out of our workouts, we need to ensure that we give our bodies the best possible support. That’s why many athletes turn to supplements to help them reach their goals. One of MucleMeds supplements that is gaining popularity among athletes and gymgoers alike is Stemptropin, a stem cell -supporting supplement designed to boost muscular hypertrophy, strength, and recovery. In this article, we’ll take a look at how Stemptropin works and the benefits it provides. Introduction to Stem Cells Stem cells are unspecialized cells that can transform into specialized cells with particular functions. In the body, stem cells help to repair and renew damaged cells. Stem cells also stimulate the release of natural growth factors. For athletes, they can help to speed up recovery after intense workouts and reduce muscle soreness. Many professional athletes undergo stem cell treatments, however these treatments are not an easy or affordable option for most of us. Stemptropin is a natural stem cell-supporting supplement designed to increase the production and  improve the function and health of athletes' stem cells, in turn boosting muscular hypertrophy, strength, and recovery. How Stemptropin Works Stemptropin works in part by stimulating stem cells to signal for the release of growth factors, which are proteins and nutrients that help to regulate various cellular activities. These growth factors help to promote the growth of muscle cells and increase muscle mass. Stemptropin also helps to reduce inflammation, which can occur after strenuous exercise. This can help to speed up recovery and reduce muscle soreness. Additionally, Stemptropin signals for stem cells to aid the production of collagen, which is a protein that provides structure and strength to the muscles. This can help to boost performance and reduce the risk of injury. Stemptropin is a powerful, natural supplement working to boost muscular hypertrophy, strength, and recovery through the power of stem cells.  Stemtropin and Muscular Hypertrophy Muscular hypertrophy is a process in which muscle cells grow in size and number. For hypertrophy to happen, muscle fibers must undergo damage and microtears through resistance training. The healing process following this damage is where hypertrophy happens, and stem cells play a central role in this recovery process. This is important for athletes and gymgoers who are looking to build serious muscle mass. As touched on earlier, stemptropin helps to increase muscular hypertrophy by increasing growth factors and signals for stem cell proliferation in muscle fibers. These new stem cells in the muscle fibers can transform into new muscle tissue. This new muscle tissue can be stimulated in the gym, creating a bigger, stronger overall muscle.  Stemptropin and Muscular Strength Stem cells have been found to be an extremely powerful tool to increase muscle strength. Not only does stemptropin help signal for stem cells to travel to the muscle fibers, but it helps to boost the production of collagen, a key structural component of muscle tissue that gives it its strength and shape. This is a great benefit for athletes, bodybuilders, and anyone else looking to increase their strength and improve their performance. Stemptropin works by mobilizing stem cells and encouraging them to differentiate into new, healthy cells within the body. This process stimulates collagen production, which helps to increase muscle mass, strength, and endurance. It also helps to reduce inflammation and improve joint mobility. All of these effects can lead to significant gains in overall muscle strength. With stemptropin, the possibilities are endless for athletes, gymgoers, and bodybuilders alike who are looking for maximum results. Stemptropin and Muscular Recovery and Injury Prevention Stemptropin can also help to prevent injuries to muscle tissue. The same increase in collagen production that was touched on earlier, which provides structure and strength to the muscles, provides a protective quality to muscle tissue, reducing the likelihood of muscle injuries. Additionally, Stemptropin can help to improve recovery. This is because stemtropin helps to reduce inflammation, which can in turn speed up the recovery process, and reduce the muscle soreness that is so commonly experienced after a hard training session. Conclusion Stemptropin is a natural supplement designed, and proven to boost stem cell function, which in turn may improve muscular hypertrophy, strength, and recovery by optimizing stem cell activity in the muscle. It works by stimulating stem cells for the release of stem cell growth factors to improve muscular strength and size while increasing collagen production to help prevent muscular injuries. Stemptropin can be taken pre-workout or before bed time as part of your supplement regimen to maximize muscular hypertrophy, strength, and recovery. With the right supplement and exercise program, you can reach your fitness goals faster and more effectively.   CLICK HERE to learn how STEMTROPIN can help you boost stem cells. 

Akim Williams Training Tip: Flat Bench Fly

Akim Williams Training Tip: Tricep Extensions

An Introduction to Stem Cells, and Stem Cell Optimization

Welcome to the first installment of our series on stem cells and sports nutrition! We'll be discussing the basics of stem cells and their importance in maintaining overall health and supporting muscle growth and recovery. So, what are stem cells exactly? Stem cells are special types of cells that have the ability to develop into a variety of different cell types in the body. They are the focus of cutting-edge regenerative medicine because they can repair and regenerate damaged tissue, and they play a crucial role in maintaining the health and function of our organs and tissues. There are a few types of stem cells: embryonic stem cells and adult stem cells. Embryonic stem cells are derived from the inner cell mass of a blastocyst, a hollow ball of cells that forms in the early stages of human development. These cells have the ability to develop into any type of cell in the body, and they are therefore considered to be pluripotent. Adult stem cells, on the other hand, are found in various tissues and organs throughout the body. The type of stem cell most commonly used in medical treatments are mesenchymal stem cells. Mesenchymal stem cells are a type of adult stem cell, found in various tissues and organs throughout the body, including bone marrow, adipose tissue, and umbilical cord blood. Mesenchymal stem cells have the ability to differentiate into several different cell types, including muscle cells, bone cells, and cartilage cells. They are often used in regenerative medicine due to their ability to promote tissue repair and regeneration. Mesenchymal stem cells have been studied for their potential use in a variety of conditions, including muscle injuries, osteoarthritis, and cardiovascular disease. Stem cells are able to repair and regenerate damaged tissue by dividing and producing new cells. This process, known as cell division, occurs when a stem cell divides into two daughter cells. One of the daughter cells will remain a stem cell, while the other will differentiate into a specific type of cell, such as a muscle cell or a nerve cell. The number of stem cells in the body decreases as we age. This is thought to be one of the factors that contribute to the decline in our physical and cognitive function as we get older. Some researchers believe that by increasing the number of stem cells in the body, it may be possible to slow down or even reverse this decline. As athletes and bodybuilders, the health and function of our muscles are of particular importance. That's where stem cells come in. Stem cells are involved in the process of rebuilding and repairing muscle tissue after it has been damaged by exercise. When we engage in activities such as weight training, our muscles undergo microtrauma, which is small amounts of damage to the muscle fibers. This damage is necessary for muscle growth and adaptation, but it also requires repair. Stem cells play a central role in this repair process by dividing and producing new muscle cells to replace the damaged ones. There are several ways to support an internal environment that is conducive to stem cell health. Some of these include: Fasting: Fasting has been shown to stimulate the production of stem cells. This can be done through intermittent fasting, where you eat all of your meals within a specific window of time, or through longer fasts, such as a 24-hour fast once or twice a week. Reducing sugar consumption: High sugar intake can damage stem cells and inhibit their function. Limiting your intake of added sugars and refined carbs can help to support stem cell health. Exercise: Regular exercise has been shown to increase the number of stem cells in the body. In addition to the well-known benefits of exercise for muscle health and function, it may also support stem cell health and regeneration. Supporting healthy inflammation: Supporting healthy inflammation through a balanced diet and proper lifestyle management. This includes getting enough antioxidants through a varied diet, managing stress, and getting enough sleep. There are also natural supplements that support stem cell health and function. MuscleMeds Stemptropin contains a variety of ingredients including L-Dopa and Sea Buckthorn Fruit Extract. In a clinical study, Sea Buckthorn was shown to increase stem cells by 20%. Other Studies have shown that L-dopa can stimulate the proliferation and differentiation of stem cells, including mesenchymal stem cells. It has also been shown to promote the formation of new blood vessels, which can support the growth and development of new tissues. L-dopa and Sea Buckthorn Fruit Extract have both been shown to have a number of other beneficial effects for stem cells, including reducing oxidative stress and inflammation and promoting cell survival and longevity. These effects may be mediated by the ability of L-dopa and Sea Buckthorn Fruit Extract to affect signaling pathways and gene expression in stem cells. Including MuscleMeds Stemtropin in your supplement stack is a surefire way to improve the function and health of the stem cells in your body.  In conclusion, stem cells are vitally important for maintaining the health and function of our tissues and organs, including our muscles. By supporting an internal environment that is conducive to stem cell health through methods such as fasting, reducing sugar consumption, exercising, and proper supplementation, we can help to support overall stem cell integrity and muscle recovery. As bodybuilders, it's important to consider the role that stem cells play in muscle repair and regeneration and to consider ways to support their health and function. In future articles in our series, we'll be diving into the role of stem cells in various tissue types and how we can support their health and function. Stay tuned for more information on the role of stem cells in muscle strength and size, maintaining connective tissue and joint health, and the role of stem cells in recovering from injury and surgery. In the meantime, consider incorporating some of the strategies we've discussed here, and MuscleMeds Stemtropin to support stem cell health and function and maintain optimal overall health and muscle function. CLICK HERE to learn how STEMTROPIN can help you boost stem cells. 

Akim Williams Training Tip: Dumbbell Curls

Stem Cell Research

STEM CELL RESEARCH IS MAKING NOISE IN THE SUPPLEMENT INDUSTRY   Stem cells have been a hot topic in the field of medicine and biology for several decades now. They have the unique ability to develop into different cell types in the body and can be used to treat a wide range of diseases and injuries. Current and former Olympians, CBUM and RAMY, have gone viral discussing how stem cells can be used to improve recovery.  CBUM AND HIS STEM CELL USE  CBUM tells his untold story about stem cell recovery while he focuses on the role of stem cells in the repair and regeneration of muscle. Recently suffering from a bicep injury, CBUM has turned to stem cells to advance his recovery to get him back into his peak form. He has found that muscle stem cells, also known as satellite cells, play a crucial role in muscle repair and growth. CBUM's viral video has brought tremendous attention to stem cell repair in the fitness industry.   RAMY’S TAKE ON STEM CELLS FOR INJURIES  RAMY, on the other hand, focuses on the use of stem cells in the treatment of injuries and damaged nerves. He has found that stem cells can differentiate into various cell types, such as muscle, nerve, and bone cells. This means that stem cells can be used to repair or replace damaged or diseased cells in the body.   MUSCLEMED’S STEMTROPIN IS AN EFFECTIVE STEM CELL SUPPLEMENT  MuscleMeds, a company that produces nutritional supplements, has recently introduced a new product called STEMTROPIN. This product is designed to increase the number of stem cells in the body, which can lead to faster recovery and improved muscle growth. STEMTROPIN contains a blend of ingredients that have been shown to stimulate the production of stem cells including Sea Buckthorn, Safed Musli, and Mucuna. STEMTROPIN, can be a powerful tool for athletes and bodybuilders who want to improve their recovery and muscle growth. By increasing the number of stem cells in the body, STEMTROPIN can help to speed up the repair and regeneration of muscle tissue, leading to faster recovery and better performance. Additionally, the ability of stem cells to differentiate into various cell types means that they can also be used to treat injuries and diseases.  CLICK HERE to learn how STEMTROPIN can help you boost stem cells. 
Supplements

Supplement Spotlight: Vitamin T

It’s been said that a dog is man’s best friend, but that moniker really should be bestowed upon the powerful and seemingly omnipotent testosterone. Testosterone is a critical male hormone that plays a key role in a man’s physical and sexual performance. In fact, it has a plethora of important functions. Receptors for testosterone are found in almost all tissues, and it contributes to lean body mass, bone health, cognitive function and mood, and the production of sperm. It makes sense that a guy would want his multivitamin to enhance his testosterone. So, what’s the best solution? VITAMIN T™ from MuscleMeds, a premium testosterone-enhancing complete multivitamin specially formulated for men. Enhance Testosterone Naturally Higher testosterone levels will help you build more muscle, recover faster and perform better in the bedroom. Low testosterone, on the other hand, can result in erectile dysfunction, reduced bone mass and sex drive, loss of muscle, increased body fat and lethargy. Seems like a no-brainer: No man should ever ignore the importance of proper nutrition and supplementation to support healthy testosterone levels for optimal male performance. The research and development team at MuscleMeds has formulated VITAMIN T™ with clinically researched herbs and minerals and potent antioxidants to enhance testosterone naturally, to improve physical and sexual performance. Boost Free Testosterone in 7 Days VITAMIN T™ contains 500 milligrams of Fenugreek, 200 milligrams of Tribulus, 100 milligrams of Longjack and 200 milligrams Boron Citrate, that have been shown to significantly boost free testosterone in just seven days. VITAMIN T™ also contains potent antioxidants such as vitamins C and E to support the immune system and optimal male health. Look, Feel and Perform at Your Best The choice is yours: you can get up every day and choose to be the best version of yourself possible, directing your own course in life to one of optimal health and performance. If you want to look, feel and perform at your best, VITAMIN T™ is the multivitamin for you.  Reference: Naghii MR, Mofid M et al. Comparative effects of daily and weekly boron supplementation on plasma steroid hormones and proinflammatory cytokines. Physiology and Pharmacology 2011; 15 (3), 403-414. VITAMIN T™ Natural Testosterone Enhancement  Supports Lean Muscle Improves Performance Enhances Libido 20 Vitamins and Minerals  Potent Antioxidants    High Potency Multivitamin for Men 500 mg Fenugreek 200 mg Tribulus 200 mg Boron Citrate 100 mg Longjack  
Supplements

Why Every Man Should Take VITAMIN T

Plenty of things are sagging and dropping these days, but even worse than some parts of your body or the stock market is your level of total testosterone. Testosterone levels have decreased steadily for decades among young U.S. men between past and current generations. And research demonstrates that the critical male hormone testosterone starts to drop in adolescence – this is not just a problem for men in their 50s. How do you fight back and win the war against low T? Arm yourself with VITAMIN T™. Because testosterone plays a key role in a man’s physical and sexual performance, it’s important that all men address healthy testosterone levels, which is why MuscleMeds developed VITAMIN T™ – a premium testosterone-support formula and complete multivitamin specially formulated for men.†  Enhance Testosterone Naturally Testosterone has a plethora of important functions. Receptors for testosterone are found in almost all tissues, and it contributes to lean body mass, bone health, cognitive function and mood, and the production of sperm. VITAMIN T™ is a high-potency multivitamin formulated to provide natural testosterone support.† Higher testosterone levels will help you build more muscle, recover faster and perform better in the bedroom. Low testosterone, on the other hand, can result in erectile dysfunction, reduced bone mass and sex drive, loss of muscle, increased body fat and lethargy. Seems like a no-brainer: No man should ever ignore the importance of proper nutrition and supplementation to support healthy testosterone levels for optimal male performance. The research and development team at MuscleMeds has formulated VITAMIN T™ with clinically researched herbs and minerals and potent antioxidants to support testosterone naturally, to improve physical and sexual performance.†   Your T Levels Are Dropping You may not realize it, but your testosterone levels are dropping as you read this. According to results presented at the 2020 American Urological Association Virtual Experience and reported in Urology Times Journal, testosterone levels have declined in adolescent and young adult men (AYA) from 1999 to 2016. Put another way, today’s men are not the men their fathers were in the testosterone department. And the decline in total testosterone was observed even among men with normal body mass index – so dropping testosterone is happening regardless of whether you are carrying a few extra pounds. Lokeshwar et al. used data from the National Health and Nutrition Examination Surveys (NHANES) from 1999 to 2016 to analyze serum testosterone level changes over time in 4,045 young adult men aged 15 through 39. After controlling for confounders – including year of study, age, race, BMI, comorbidity status, alcohol and smoking use, and level of physical activity – researchers found that total testosterone was lower among men in later (2015-2016) versus earlier (1999-2000) years.   ‘Very scary’ Testosterone deficiency has a prevalence of 20% among adolescent and young adult males. Although previous studies have shown that total testosterone (TT) levels are declining in the population compared to prior decades, Lokeshwar et al. identified falling TT levels for AYA males specifically. “This is especially worrisome in this young adult age group, as many men feel stigma and are less likely to seek care for low libido and erectile dysfunction,” said Soum Lokeshwar, MD, MBA of the Yale School of Medicine. “Testosterone levels in AYA men are used as the benchmark normal levels for testosterone,” Lokeshwar continued. “This is very scary, because generally, when we think of normal values of testosterone, we treat based upon this age group. This may ultimately lead to the undertreatment of testosterone deficiency, which can have large ramifications and severe consequences.” What Causes Low T? Lokeshwar said possible causes for TT declines could be a result of obesity and declines in exercise and physical activity, and higher body fat percentages. “We’ve seen that lower values of testosterone have been associated with increased comorbidities and an increase risk for all-cause mortality. This decline specifically, in these young adult men, with increased obesity may lead to an increase in precocious cancer,” Lokeshwar said, adding such decreases can also result in a lower libido and an increased risk for erectile dysfunction. Other causes of lower testosterone in younger men may include fasting, low-fat diets, ketogenic diets, overtraining, alcohol, statins (cholesterol-lowering drugs), chronic stress, lack of sleep, and environmental endocrine disruptors such as Bisphenol A (in polycarbonate plastics) and Phthalates (found in plastics and many cosmetics). For testosterone support, VITAMIN T™ contains 500 milligrams of Fenugreek, 200 milligrams of Tribulus, 100 milligrams of Longjack and 200 milligrams Boron Citrate.† VITAMIN T™ also contains potent antioxidants such as vitamins C and E to support the immune system and optimal male health.† Look, Feel and Perform at Your Best The choice is yours: you can get up every day and choose to be the best version of yourself possible, directing your own course in life to one of optimal health and performance. If you want to look, feel and perform at your best, VITAMIN T™ is the multivitamin for you. †These statements have not been evaluated by the U.S. Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. VITAMIN T™ Natural Testosterone Support  Supports Lean Muscle Improves Performance Enhances Libido 20 Vitamins and Minerals  Potent Antioxidants    High Potency Multivitamin for Men 500 mg Fenugreek 200 mg Tribulus 200 mg Boron Citrate 100 mg Longjack References: Naghii MR, Mofid M et al. Comparative effects of daily and weekly boron supplementation on plasma steroid hormones and proinflammatory cytokines. Physiology and Pharmacology 2011; 15 (3), 403-414. Kristie L Kahl. Urology Times Journal, July 3, 2020; Vol 48 No 7, Volume 48, Issue 07. Soum D Lokeshwar, et al. Decline in Serum Testosterone Levels Among Adolescent and Young Adult Men in the USA. Eur Urol Focus, 2021 Jul;7(4):886-889. Shufa Zheng et al. Serum level of testosterone predicts disease severity of male COVID-19 patients and is related to T-cell immune modulation by transcriptome analysis. Clin Chim Acta, 2022 Jan 1;524:132-138. A Klibanski et al. Reproductive function during fasting in men. J Clin Endocrinol Metab, 1981 Aug;53(2):258-63. Tatiana Moro et al. Effects of eight weeks of time-restricted feeding (16/8) on basal metabolism, maximal strength, body composition, inflammation, and cardiovascular risk factors in resistance-trained males. Journal of Translational Medicine, volume 14, Article number 290 (2016) Anthony C Hackney. Hypogonadism in Exercising Males: Dysfunction or Adaptive-Regulatory Adjustment? Front Endocrinol, 31 January 2020. DM Kelly et al. Testosterone and obesity. Obes Rev, 2015 Jul. M Diaz-Arjonilla et al. Obesity, low testosterone levels and erectile dysfunction. Int J Impot Res, Mar-Apr 2009. Mark Ng Tang Fui et al. Lowered testosterone in male obesity: mechanisms, morbidity and management. Asian J Androl, Mar-Apr 2014. Overweight men can boost low testosterone levels by losing weight. Endocrine Society; June 25, 2012. Haibo Jin et al. Chronic exposure to polystyrene microplastics induced male reproductive toxicity and decreased testosterone levels via the LH-mediated LHR/cAMP/PKA/StAR pathway. Part Fibre Toxicol, 2022. Pai Zheng et al. Association between ambient air pollution and blood sex hormones levels in men. Environmental Research, Volume 211, August 2022. Reduced testosterone tied to endocrine-disrupting chemical exposure. Endocrine Society, August 14, 2014. Ylenia Duca et al. Substance Abuse and Male Hypogonadism. J Clin Med, 2019 May 22;8(5):732. Tzu-Yu Hu et al. Testosterone-Associated Dietary Pattern Predicts Low Testosterone Levels and Hypogonadism. Nutrients, 2018 Nov; 10(11): 1786. Joseph Whittaker et al. Low-fat diets and testosterone in men: Systematic review and meta-analysis of intervention studies. J Steroid Biochem Mol Biol, 2021 Jun. Hideyuki Imai et al. Secondary Hypogonadism due to Excessive Ingestion of Isoflavone in a Man. Intern Med 2022. Maarten C Bosland et al. Impact of 18-Month Soy Protein Supplementation on Steroid Hormones and Serum Biomarkers of Angiogenesis, Apoptosis, and the Growth Hormone/IGF-1 Axis: Results of a Randomized, Placebo-Controlled Trial in Males Following Prostatectomy. Nutr Cancer, 2022;74(1):110-121. Xiaofan Xiong et al. Chronic stress inhibits testosterone synthesis in Leydig cells through mitochondrial damage via Atp5a1. J Cell Mol Med, 2022 Jan;26(2):354-363. Sleep loss dramatically lowers testosterone in healthy young men. ScienceDaily, JAMA and University of Chicago Medical Center, June 1, 2011. Rachel Leproult, Ph.D. and Eve Van Cauter, Ph.D. Effect of 1 Week of Sleep Restriction on Testosterone Levels in Young Healthy Men. JAMA. 2011;305(21):2173-2174.  

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