MuscleMeds

MUSCLEMEDS IS EXCITED TO ANNOUNCE THE RELEASE OF ITS NEW AROMATASE INHIBITOR AROMATEST! It’s no secret, testosterone is the holy grail for muscle building and male performance. That’s why bodybuilders and athletes are constantly seeking ways to increase testosterone. However, if you want to get the best results and build hard dense muscle, you should understand a process known as aromatization. WARNING: Increasing Testosterone Can Also Increase Your Estrogen! What is Aromatization? Aromatization is a process that converts testosterone into estrogen. The reason this process is called aromatization is because the chief enzyme involved in the conversion of testosterone to estrogen is called the aromatase enzyme. A shocking fact is 80% of the estrogen is men is derived from the aromatization of testosterone. Aromatization occurs when the body is attempting to maintain homeostasis (balance) between testosterone and estrogen, this is referred to your testosterone to estrogen (T:E) ratio. So, when you elevate your body’s production of testosterone or increase your testosterone levels naturally with testosterone boosting supplements it can lead to aromatization and increased estrogen. Athletes using androgenic anabolic steroids (AAS) often experience high levels of aromatization and conversion of testosterone to estrogen. This is not the desired effect you want as elevated estrogen can cause undesirable side effects such as increased body fat, water retention, low libido, and enlarged breast tissue, also known as gynecomastia.   So, wouldn’t it be great if you could reduce the aromatization of your testosterone to estrogen and boost your test levels higher? Many pro bodybuilders and athletic trainers are aware of how to avoid this by using aromatase inhibitors during their cycles. They know that to achieve a hard dense muscular physique, they must prevent the aromatization of testosterone to estrogen. Many bodybuilders use pharmaceutical aromatase inhibitors (AIs) to reduce this conversion and alleviate unsightly and problematic issues. But now, there is a natural solution AROMATEST, bodybuilding’s most powerful natural aromatase inhibitor! CUTTNG EDGE RESEARCH: AROMATEST COMBINES NATURE’S MOST POWERFUL AROMATASE INHIBITORS XN AND 8-PN WITH AN ADVAVNCED LIPOPHILIC DELIVERY SYSTEM! The medical research has proven the effectiveness of aromatase inhibitors for reducing the conversion of testosterone to estrogen, which has many positive benefits for men and especially for bodybuilders and athletes. MUSCLEMEDS researchers have spent the past several years working on the development of an efficacious natural aromatase inhibitor. They reviewed thousands of potential compounds and after years of research they have developed, AROMATEST, the powerhouse of natural aromatase inhibitors. AROMATEST is formulated with a proprietary prenylflavonoid extract of Xanthohumol (XN) and 8-prenylnaringenin (8-PN). Research shows these two natural compounds are the most powerful aromatase inhibitors. To further improve the potency and efficacy of these compounds, AROMATEST uses a super-bioavailable lipophilic delivery system making Its effectiveness unparalleled. Research shows it’s advanced delivery system provides superior bioavailability and efficacy, with 20x greater absorption. AROMATEST has also been shown to slow down the metabolism of testosterone keeping testosterone levels elevated for a longer period of time. Who Can Benefit From AROMATEST? AROMATEST can help a wide array of men. 1. Natural athletes looking to enhance testosterone and improve their T:E ratio can take AROMATEST. Also, natural athletes taking testosterone boosting supplements to boost test levels should also consider taking AROMATEST to prevent the conversion to estrogen. 2. Of course, as we have covered AROMATEST can be extremely beneficial for athletes using AAS to reduce the testosterone and other anabolic androgens they are taking from converting to estrogen during cycles. It can also be helpful for PCT (post cycle therapy) to help prevent off cycle crash often seen with the rapid unfavorable shift in T:E after a cycle.  3. AROMATEST can also benefit men over 40. As men age, their testosterone begins to decline and they experience an unfavorable shift in their T: E ratio. Many physicians are using aromatase inhibitors to help increase the production of testosterone, reduce the conversion to estrogen and improve the T:E ratio. AROMATEST offers men a natural alternative.     Now, you can experience for yourself how the top pro bodybuilders are able to build rock hard muscle. The key is to block testosterone’s conversion to estrogen with AROMATEST!   Build Muscle Reduce Body Fat Reduce Water Retention Increase Libido   Shop Now

Anthropometry: Determining Your Muscle Potential By: Aaron Wellman, PhD MS Nutrition Science and Applied Sports Science What is Anthropometry? Muscle is always a key focus here at MuscleMeds. One thing we already know is muscle size and structure play a critical role in sports and athletic performance. Most people have no idea what their size and muscle growth potential is. As an athlete wouldn’t it be great to know?   Anthropometry is a term that describes the systematic approach of objectively classifying components of the human body, based upon joint, limb, torso and the whole body dimensions and structural characteristics, utilizing standardized measurement techniques (Kalayci et al., 2016). For many years, it has been postulated that body structure plays a critical role in athletic performance (Malina, 1975) and, to this end, these measures are being used to establish to how, and to what extent, they impact muscle growth potential and physical performance. NFL, NBA, and NHL Improve Performance & Mitigate Risk of Injury A novel study (Martin, AD. (1984) performed several years ago, which involved the complete dissection of cadavers, has provided the framework to accurately measure the masses of an individual’s skeletal mass, muscle mass, and fat mass, in addition to skin and organ mass. This anatomical assessment involves 25 measures, including measures of bone breadths, skinfolds, and limb girths, allowing us to determine, among other variables, the maximal amount of muscle mass that an individual is able to carry. Sports organizations, including the NFL, NBA, and NHL are now utilizing these measures to determine the optimal amount of muscle mass for their athletes, which may improve performance and mitigate the risk of injury. The Impact on Athletes & Fitness Enthusiasts For fitness enthusiasts not participating in organized sport, this quick assessment not only determines the current level of muscle mass and body fat, but also provides reliable information on how much more muscle mass the frame can carry. Armed with this information, training recommendations and nutritional protocols are then prescribed to achieve the specific fitness and/or bodybuilding goals of each individual. This assessment massive implications for athletes and nonathletes alike, who are interested in increasing performance, improving body composition, or achieving high levels of muscularity. Subsequent articles will focus on specific nutrition, supplementation, training strategies to achieve each of these desired goals.  

Plenty of things are sagging and dropping these days, but even worse than some parts of your body or the stock market is your level of total testosterone. Testosterone levels have decreased steadily for decades among young U.S. men between past and current generations. And research demonstrates that the critical male hormone testosterone starts to drop in adolescence – this is not just a problem for men in their 50s. How do you fight back and win the war against low T? Arm yourself with VITAMIN T + NITROTEST. Because testosterone plays a key role in a man’s physical and sexual performance, it’s important that all men address healthy testosterone levels, which is why MuscleMeds developed VITAMIN T & NITROTEST. This pair of supplements provides premium testosterone-support, a complete daily multivitamin, and a heavy-hitting pre-workout specially formulated for men.†  ENHANCE TESTOSTERONE NATURALLY Testosterone has a plethora of important functions. Receptors for testosterone are found in almost all tissues, and it contributes to lean body mass, bone health, cognitive function and mood, and the production of sperm. NITROTEST is a 2-in-1 hardcore pre-workout supplement with natural testosterone boosters. VITAMIN T is a high-potency multivitamin formulated to provide natural testosterone support.† Higher testosterone levels will help you build more muscle, recover faster and perform better in the bedroom. Low testosterone, on the other hand, can result in erectile dysfunction, reduced bone mass and sex drive, loss of muscle, increased body fat and lethargy. Seems like a no-brainer: No man should ever ignore the importance of proper nutrition and supplementation to support healthy testosterone levels for optimal male performance. The research and development team at MuscleMeds has formulated VITAMIN T and NITROTEST with clinically researched herbs and minerals and potent antioxidants to support testosterone naturally, to improve physical and sexual performance.† YOUR T LEVELS ARE DROPPING You may not realize it, but your testosterone levels are dropping as you read this. According to results presented at the 2020 American Urological Association Virtual Experience and reported in Urology Times Journal, testosterone levels have declinedin adolescent and young adult men (AYA) from 1999 to 2016.  Because testosterone plays a key role in a man’s physical and sexual performance, it’s important that all men address healthy testosterone levels. Put another way, today’s men are not the men their fathers were in the testosterone department. And the decline in total testosterone was observed even among men with normal body mass index – so dropping testosterone is happening regardless of whether you are carrying a few extra pounds. Lokeshwar et al. used data from the National Health and Nutrition Examination Surveys (NHANES) from 1999 to 2016 to analyze serum testosterone level changes over time in 4,045 young adult men aged 15 through 39. After controlling for confounders – including year of study, age, race, BMI, comorbidity status, alcohol and smoking use, and level of physical activity – researchers found that total testosterone was lower among men in later (2011-2016) versus earlier (1999-2000) years. Mean total testosterone decreased from 1999-2000 (605.39 ng/dL), 2003-2004 (567.44 ng/dL), 2011-2012 (424.96 ng/dL), 2013-2014 (431.76 ng/dL) and 2015-2016 (451.22 ng/dL). ‘VERY SCARY’ Testosterone deficiency has a prevalence of 20% among adolescent and young adult males. Although previous studies have shown that total testosterone (TT) levels are declining in the population compared to prior decades, Lokeshwar et al. identified falling TT levels for AYA males specifically. “This is especially worrisome in this young adult age group, as many men feel stigma and are less likely to seek care for low libido and erectile dysfunction,” said Soum Lokeshwar, MD, MBA of the Yale School of Medicine. “Testosterone levels in AYA men are used as the benchmark normal levels for testosterone,” Lokeshwar continued. “This is very scary, because generally, when we think of normal values of testosterone, we treat based upon this age group. This may ultimately lead to the undertreatment of testosterone deficiency, which can have large ramifications and severe consequences.” WHAT CAUSES LOW T? Lokeshwar said possible causes for TT declines could be a result of obesity and declines in exercise and physical activity, and higher body fat percentages. “We’ve seen that lower values of testosterone have been associated with increased comorbidities and an increase risk for all-cause mortality. This decline specifically, in these young adult men, with increased obesity may lead to an increase in precocious cancer,” Lokeshwar said, adding such decreases can also result in a lower libido and an increased risk for erectile dysfunction. Other causes of lower testosterone in younger men may include fasting, low- fat diets, ketogenic diets, overtraining, phytoestrogens from soy, alcohol, statins (cholesterol-lowering drugs), chronic stress, lack of sleep, and environmental endocrine disruptors such as Bisphenol A (in polycarbonate plastics) and Phthalates (found in plastics and many cosmetics). For testosterone support, VITAMIN T contains 500 milligrams of Fenugreek, 200 milligrams of Tribulus, 100 milligrams of Longjack and 200 milligrams Boron Citrate.† VITAMIN T also contains potent antioxidants such as vitamins C and E to support the immune system and optimal male health.† LOOK, FEEL AND PERFORM AT YOUR BEST The choice is yours: you can get up every day and choose to be the best version of yourself possible, directing your own course in life to one of optimal health and performance. If you want to look, feel and perform at your best, VITAMIN T is the multivitamin for you. †These statements have not been evaluated by the U.S. Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. References:1. Naghii MR, Mofid M et al. Comparative effects of daily and weekly boron supplementation on plasma steroid hormones and proinflammatory cytokines. Physiology and Pharmacology 2011; 15 (3), 403-414. 2. Kristie L Kahl. Urology Times Journal, July 3, 2020; Vol 48 No 7, Volume 48, Issue 07. 3. Soum D Lokeshwar, et al. Decline in Serum Testosterone Levels Among Adolescent and Young Adult Men in the USA. Eur Urol Focus, 2021 Jul;7(4):886-889. 4. Shufa Zheng et al. Serum level of testosterone predicts disease severity of male COVID-19 patients and is related to T-cell immune modulation by transcriptome analysis. Clin Chim Acta, 2022 Jan 1;524:132-138. 5. A Klibanski et al. Reproductive function during fasting in men. J Clin Endocrinol Metab, 1981 Aug;53(2):258-63. 6. Tatiana Moro et al. Effects of eight weeks of time-restricted feeding (16/8) on basal metabolism, maximal strength, body composition, inflammation, and cardiovascular risk factors in resistance-trained males. Journal of Translational Medicine, volume 14, Article number 290 (2016) 7. Anthony C Hackney. Hypogonadism in Exercising Males: Dysfunction or Adaptive- Regulatory Adjustment? Front Endocrinol, 31 January 2020. 8. DM Kelly et al. Testosterone and obesity. Obes Rev, 2015 Jul. 9. M Diaz-Arjonilla et al. Obesity, low testosterone levels and erectile dysfunction. Int J Impot Res, Mar-Apr 2009. 10. Mark Ng Tang Fui et al. Lowered testosterone in male obesity: mechanisms, morbidity and management. Asian J Androl, Mar-Apr 2014. 11. Overweight men can boost low testosterone levels by losing weight. Endocrine Society; June 25, 2012. 12. Haibo Jin et al. Chronic exposure to polystyrene microplastics induced male reproductive toxicity and decreased testosterone levels via the LH-mediated LHR/cAMP/PKA/StAR pathway. Part Fibre Toxicol, 2022. 13. Pai Zheng et al. Association between ambient air pollution and blood sex hormones levels in men. Environmental Research, Volume 211, August 2022. 14. Reduced testosterone tied to endocrine- disrupting chemical exposure. Endocrine Society, August 14, 2014. 15. Ylenia Duca et al. Substance Abuse and Male Hypogonadism. J Clin Med, 2019 May 22;8(5):732. 16. Tzu-Yu Hu et al. Testosterone-Associated Dietary Pattern Predicts Low Testosterone Levels and Hypogonadism. Nutrients, 2018 Nov; 10(11): 1786. 17. Joseph Whittaker et al. Low-fat diets and testosterone in men: Systematic review and meta- analysis of intervention studies. J Steroid Biochem Mol Biol, 2021 Jun. 18. Hideyuki Imai et al. Secondary Hypogonadism due to Excessive Ingestion of Isoflavone in a Man. Intern Med 2022. 19. Maarten C Bosland et al. Impact of 18-Month Soy Protein Supplementation on Steroid Hormones and Serum Biomarkers of Angiogenesis, Apoptosis, and the Growth Hormone/IGF-1 Axis: Results ofa Randomized, Placebo-Controlled Trial in Males Following Prostatectomy. Nutr Cancer, 2022;74(1):110- 121.20. Xiaofan Xiong et al. Chronic stress inhibits testosterone synthesis in Leydig cells through mitochondrial damage via Atp5a1. J Cell Mol Med, 2022 Jan;26(2):354-363. 21. Sleep loss dramatically lowers testosterone in healthy young men. ScienceDaily, JAMA and University of Chicago Medical Center, June 1, 2011. 22. Rachel Leproult, Ph.D. and Eve Van Cauter, Ph.D. Effect of 1 Week of Sleep Restriction on Testosterone Levels in Young Healthy Men. JAMA. 2011;305(21):2173-2174.